Sunday, July 13, 2008

Glioblastoma

A Glioblastoma is a type of a primary brain tumor. Primary brain tumors are those that arise from the brain itself rather than traveling or metastasizing from another location in the body. Approximately 17,000 new cases of primary brain tumors are treated each year in the United States.

Primary brain tumors can either be benign or malignant. Benign brain tumors (eg. meningiomas, acoustic neuromas, pituitary gland tumors) usually grow slowly and can often be removed by surgery depending upon their specific location in the brain. Malignant brain tumors, such as glioblastomas and anaplastic astrocytomas, among others, tend to grow rapidly spreading into the surrounding brain tissue and often cannot be entirely removed surgically.

Primary brain tumors can occur in both children as well as adults. The most common age groups are children 3 to 12 and adults ages 40-70. Metastatic brain tumors, such as glioblastomas, are much more common in adults than in children.

There are many different types of brain tumors. One type, know as astrocytomas, are tumors that arise from astrocyte cells - part of the supportive (neuroglial) tissue of the brain. Astrocytomas account for about half of all primary brain and spinal cord tumors.
Glioblastomas are fast growing astrocytomas that contain areas of dead (necrotic) tumor cells. In adults, glioblastoma occurs most often in the cerebrum, especially in the frontal and temporal lobes of the brain. They rarely occur in the cerebellum or brain stem.
Glioblastoma can be difficult to treat although surgery, radiation therapy, steroids, and chemotherapy have shown the ability to prolong survival.

Source: MediFocus.Com

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